Operational Tools and Best Practices to Support Electronic Health Record-Sourced Data Quality, Relevance, and Reliability at the Data Accrual Phase

Matthew D’Ambrosio, Patrick Rodriguez, Nora Emmott, Rachele Hendricks-Sturrup

Natural language processing to identify suicidal ideation and anhedonia in major depressive disorder

L. Alexander Vance, Leslie Way, Deepali Kulkarni, Emily O. C. Palmer, Abhijit Ghosh, Melissa Unruh, Kelly M. Y. Chan, Amey Girdhari, Joydeep Sarkar

Negative symptoms and cognitive impairment in US patients with schizophrenia: A real-world descriptive study using the NeuroBlu database

Nadia Lipunova, Matthew Sidovar, William Horan, Christoph U. Correll, Emily O.C. Palmer, Mayowa Oyesanya, Doyoung Kim, Subina Surendran, Joannas Yeow, Alejandro Cajigal

Enhancing mental healthcare through artificial intelligence: A study of depressive disorder symptoms extraction from clinical notes with natural language processing

Deepali Kulkarni, L. Alexander Vance, Amey Girdhari, Leslie J. Way, Emily O.C. Palmer, Shweta Seth Rego

Can the evidence for sertraline in clinical trials be demonstrated in real-world clinical practice? A retrospective, observational, real-world study

Kannan Subramaniam, Pradeep Purushottamahanti, Joannas Yeow, Emily O.C. Palmer, Joshua Wong, Nadia Lipunova

Identifying patients with stable schizophrenia using electronic health records

Staci Abramsky, Kira Griffiths, Claudia Hastedt, Rashmi Patel, Rose Sisk, Nadia Lipunova, Mayowa Oyesanya, Theresa Cassidy

Real world analysis of treatment change and response in adults with attention-deficit/hyperactivity disorder (ADHD) alone and with concomitant psychiatric comorbidities: results from an electronic health record database study in the United States

Christian Liman, Jeffrey Schein, Ashley Wu, Xueyan Huang, Simran Thadani, Ann Childress, Scott H. Kollins, and Sandipan Bhattacharjee

Healthcare resource utilisation and suicidal ideation amongst adolescents in the US with posttraumatic stress disorder, major depressive disorder, and substance use disorders using electronic health records

Kelly M.Y. Chan, Li Tong Low, Joshua G. Wong, Sherwin Kuah, A. John Rush

Learning by Doing: Can Our Collective Experiences as Clinicians Improve Mental Health Care?

A. John Rush, MD, and Tony Tramontin, PhD

Predictability of buprenorphine-naloxone treatment retention: A multi-site analysis combining electronic health records and machine learning

Fateme Nateghi Haredasht et al.

Real-World Evidence to Support Causal Inference: Methodological Considerations for Non-Interventional Studies

Nora Emmott et al.

Regulatory Fit-for-Purpose Considerations for Patient-Generated Health Data

Nora Emmott et al.

The clinical global impression of severity (CGI-S): Bridging the research-practice gap

Joydeep Sarkar et al.

Real-world insights into the heterogeneity of treatment patterns and clinical outcomes in patients with post-traumatic stress disorder (PTSD)

Ashley Wu, Sandipan Bhattacharjee, Christian Liman, Xueyan Huang, Kelly Chan, L. Alexander Vance, Jyoti Aggarwal

Clinical characteristics of patients with cognitive impairment associated with schizophrenia

Theresa Cassidy et al.

Long-term patient functioning and illness burden associated with cognitive impairment and negative symptoms in schizophrenia

Kira Griffiths et al.

Psychometric evaluation and linking of the PHQ-9, QIDS-C, and VQIDS-C in a real-world population with major depressive disorder

Palmer et al.

Enhancing pre-trained contextual embeddings with triplet loss as an effective fine-tuning method for extracting clinical features from electronic health record derived mental health clinical notes

Kulkarni et al.

A novel machine learning based model for point-of-care prediction of suicide risk for patients in safety-net healthcare systems

Cynthia Claasssen, Joydeep Sarkar, Abhijit Ghosh, ShaoMin Liu, Bruno Martinez, John Rush, Kari Teigen, Sajid Shaikh, James-Michael Blackwell, Apoorva Deshpande, Julie Durand, Kosisochukwu Mora, Madi Escamilla, Olla Elbasheer, Richa Patel, Nathan Denniston, Summer Ladd, Rumsha Hafeez, Amanda Rosenberg

Demographic and clinical factors associated with recurrent psychiatric hospitalizations in adult patients with major depressive disorder (MDD)

Xueyan Huang, Christian Liman, Joshua Wong, Miguel E. Renteria, Sheryl Ker, Ashley Wu, Maxime Taquet, Augustus John Rush

Examining real-world evidence of clinical outcomes, healthcare resource utilisation and treatment patterns of patients with post-traumatic stress disorder

Abramsky et al.

Examining differences in clinical and demographic characteristics of patients with post-traumatic stress disorder across adults and paediatric subgroups

Abramsky et al.

Treatment trajectory in people with major depressive disorder from diagnosis to 12 months post-diagnosis

St.Rose et al.

Treatment trajectory in people with borderline personality disorder from diagnosis to 12 months post-diagnosis

White et al.

Clinical characteristics of people with borderline personality disorder at 12 months prior to first diagnosis and at diagnosis

White et al.

Comparative effectiveness study of paliperidone palmitate 6-month with a real-world external comparator arm of paliperidone palmitate 1-month or 3-month in patients with schizophrenia

Ibrahim Turkoz et al.

Improving Patient Subgroup Representation with Real-World Data

Nora Emmott et al.

Associations of comorbid substance use disorders with clinical outcomes in schizophrenia using electronic health record data

Rashmi Patel et al.

Real-world evidence on the burden of known side-effects of typical and atypical antipsychotic medications in patients with schizophrenia

Joshua Wong et al.

Elevated anxiety in patients with major depressive disorder

A. John Rush et al.

Identifying the treatment gap of undiagnosed tardive dyskinesia: an analysis of unstructured electronic health record data

Kira Griffiths et al.

Investigating trends of behavioral healthcare resource utilization burden in children and adolescents with suicidal symptoms in the United States: An analysis of electronic health record data

Sherwin Kuah et al.

Development of a novel transdiagnostic predictor of psychiatric hospitalization using early trajectories of the Clinical Global Impression Scale

Maxime Taquet et al.

A comparison of oral aripiprazole with an ingestible sensor to oral atypical antipsychotic treatment in a real-world setting for the risk of hospitalization in adults with schizophrenia

D. Hadzi Boskovic et al.

A real-world data analysis of Clinical Global Impression-Severity (CGI-S) as a transdiagnostic predictor of psychiatric hospitalization

Emily Palmer et al.

Real-world insights into long-acting injectable antipsychotic agent initiation in the inpatient setting and transition/continuation of care: Impact of LAI characteristics on outcomes among patients with schizophrenia

Stephen Thompson et al.

Early trajectory of clinical global impression as a transdiagnostic predictor of psychiatric hospitalisation: a retrospective cohort study

Maxime Taquet et al.

Early clinical instability and increased risk of psychiatric hospitalization: real-world evidence from an analysis of electronic health record data

Maxime Taquet et al.

Life engagement improvement following initiation of brexpiprazole treatment in patients with MDD: A naturalistic, retrospective real-world study

Christian Liman et al.

Psychiatric Healthcare Resource Utilization Following Initiation of Aripiprazole Once-Monthly: A Retrospective Real-world Study

Heidi C. Waters et al.

Gender Differences in Adult ADHD Symptoms: Network Analysis of Real-world Data

Kira Griffiths et al.

The impact of a caseload management tool (MaST) on community mental healthcare service delivery

Caroline Gadd et al.

The impact of COVID-19 on psychiatric illness severity and care delivery: A real-world data study

Emily Palmer et al.

The application of natural language processing to real-world electronic health record data to identify positive and negative symptoms in schizophrenia

Rashmi Patel et al.

Transdiagnostic Analysis of Mental Disorder Symptoms Associated with Increased Frequency of Psychiatric Hospitalization

Emily Palmer et al.

Predictors Of Hospitalization In Patients With Newly Diagnosed Major Depressive Disorder: A Real-world Evidence Study

Nicole Croteau et al.

The Impact of Executive Functioning Deficit on Illness Severity in Patients with an ADHD Diagnosis: a Real-world Data Study

Emily Palmer et al.

Antipsychotic prescribing trends in schizophrenia between 2011 and 2021: real-world data from a US electronic health record database

Kira Griffiths et al.

The Association of Comorbid Substance Use Disorders with Time to Treatment Discontinuation in Patients with Schizophrenia

Rashmi Patel et al.

Antipsychotic Treatment Patterns in Patients with Schizophrenia

Rashmi Patel et al.

Psychiatric inpatient healthcare resource utilization and treatment patterns among patients with predominant negative symptoms in schizophrenia

Rashmi Patel, Aditi Kadakia, Yida Won, Carole Dembek, Xueyan Huang, Courtney Zeni, Andrei Pikalov

A Network Analysis of Borderline Personality Disorder Symptoms: A Real-world Data (RWD), Electronic Health Record (EHR) Study

Emily Palmer et al.

Associations Between Cognitive Symptoms and Poor Clinical Outcomes in Schizophrenia: Real-world Evidence from an Electronic Health Record Study

Kira Griffiths et al.

The Impact of a Caseload Management Tool (MaST) on Community Mental Health Team Care Contacts with Mental Health Service Users

Caroline Gadd et al.

Evaluation of the Impact of the Use of a Caseload Management Tool (MaST) in Mersey Care NHS Foundation Trust

Caroline Gadd et al.

Digital Health as an Enabler for Patient-Centric, Outcome-Based Care

Nawal Roy et al.

Derivation and Validation of the Management and Supervision Tool (MaST) Risk of Crisis (RoC) Algorithm Using Electronic Health Record (EHR) Data

Rashmi Patel et al.

A Validation of The Management and Supervision Tool (MaST) to aid NHS mental health teams in identifying patients needs for either psychiatric hospital admission or home treatment

Caroline Gadd

The Management and Supervision Tool (MaST): An Electronic Crisis Risk Prediction Tool to Support Safe and Effective Mental Healthcare

Rashmi Patel et al.

NeuroBlu: A Natural Language Processing (NLP) Electronic Health Record (EHR) Data Analytic Tool to Generate Real-world Evidence in Mental Healthcare

Rashmi Patel et al.

Identifying Patients with High Burden of Positive and Negative Schizophrenia Symptoms in Electronic Health Record Data Using Natural Language Processing

Rashmi Patel et al.

Healthcare Resource Use Decreases Following Initiation of Aripiprazole 400mg Long-acting Injectable: A Real-World Electronic Health Record Database Study

Heidi C. Waters et al.

Challenges and Opportunities in the Use of Real-world Evidence to Advance Treatment Development in Behavioral Health

Scott Kollins

A Transdiagnostic, Natural Language Processing Analysis of Mental Disorder Symptom Burden Using Electronic Health Record Data

Rashmi Patel et al.

Relationship Between Polypharmacy and Clinical Functioning in Patients With ADHD: A Retrospective Analysis of Real World Data

Matthew Valko et al.

Illness Severity Associated with Comorbid Substance Use Disorders in Schizophrenia: An Electronic Health Record Study

Rashmi Patel et al.

How Effective Is Antidepressant Medication (ADM) Polypharmacy in Difficult to Treat Depression (DTD)? a Neuroblu Electronic Health Record (EHR) Report

Matthew Valko et al.

Alzheimer’s Disease: Key Insights from Two Decades of Clinical Trial Failures

C. Kwon Kim et al.

NeuroBlu, an Electronic Health Record (EHR) Trusted Research Environment (TRE) to Support Mental Healthcare Analytics with Real-world Data

Rashmi Patel et al.

Associations of Comorbid Substance Use Disorders with Healthcare Service Utilization: A Cohort Using Electronic Health Record Data

Rashmi Patel et al.

Positive and Negative Symptoms in Schizophrenia: A Natural Language Processing Study of Realworld Electronic Health Record Data

Rashmi Patel et al.

Editorial: The Gathering Storm: A U.S. Perspective on the Scientific Response to the COVID-19 Child and Adolescent Mental Health Crisis

Scott Kollins

Best Practices in the Real-world Data Life Cycle

Jordan Abdi et al.

Treatment Response and Time to Treatment Discontinuation in Young Children with ADHD: An Analysis of Real-World Data from Electronic Medical Records

Scott Kollins et al.

The Need for Real-World Evidence to Close the Behavioral Health Evidence Gap

Holmusk

Are Symptoms and Functioning Distinct Depression Treatment Targets in the Real World?

Scott Kollins, PhD et al.

Impact of Comorbid Cannabis Use Disorders in Schizophrenia: An Electronic Health Record Real World Data Study

Rashmi Patel et al.

Patient life engagement improvements associated with brexpiprazole

Soon Nan Wee et al.

Factors That Affect Patient Attrition in Buprenorphine Treatment for Opioid Use Disorder: A Retrospective Real-World Study Using Electronic Health Records

Sheryl Ker et al.

Relationship Between Polypharmacy and Clinical Functioning in Patients With ADHD: A Retrospective Analysis of Real-World Data

Matthew Valko et al.

A Neural System Dynamics Modeling Platform and its Applications in Randomized Controlled Trial Data Analysis

Nadira Hamid et al.

Natural Language Processing-Based Quantification of the Mental State of Psychiatric Patients

Sankha S. Mukherjee et al

NeuroBlu®: A Longitudinal Real-World Evidence Platform for Behavioral Health Research

Qian Chen et al.

Buprenorphine Treatment Retention in Individuals with Opioid Use Disorder: Insights from Real-World Dataset

Anisha Balani et al.

Editorial: Is Child Mental Health Research Structurally Racist?

Scott Kollins

Natural Language Processing-Based Quantification of the Mental State of Psychiatric Patients

Sankha S. Mukherjee et al.

Generalized Modeling Framework for Disease Progression in Chronic & Mental Health

Nawal Roy & Joydeep Sarkar

The Effects of Vagus Nerve Stimulation on the Course and Outcomes of Patients with Bipolar Disorder in a Treatment-resistant Depressive Episode: a 5-year Prospective Registry

R Hamish McAllister-Williams et al.

Digital Therapeutics in Asia - The Key to Managing Healthcare Costs

Yau Teng Yan & Nawal Roy

Antidepressant Regulatory Warnings, Prescription Patterns, Suicidality and Other Aggressive Behaviors in Major Depressive Disorder and Anxiety Disorders

Saurabh Gupta et al.

Use of Augmentation Agents for Treating Depression: Analysis of a Psychiatric Electronic Medical Record Data Set

Kenneth R. Gersing et al.

Co-morbid Substance Use Disorders with Other Axis I and II Mental Disorders Among Treatment-seeking Asian Americans, Native Hawaiians/Pacific Islanders, and Mixed-race People

Li-Tzy Wu et al.

Using Electronic Health Records Data to Assess Comorbidities of Substance Use and Psychiatric Diagnoses and Treatment Settings Among Adults

Li-Tzy Wu et al.

The Effectiveness of Antidepressant Monotherapy in a Naturalistic Outpatient Setting

Tih­-Shih Lee et al.

Cognitive Improvement Following Treatment in Late Life Depression: Relationship to Vascular Risk and Age of Onset

Deanna M. Barch et al.

Patient Electronic Health Data-driven Approach to Clinical Decision Support

Ketan K Mane et al.

VisualDecisionLinc: A Visual Analytics Approach for Comparative Effectiveness-based Clinical Decision Support in Psychiatry

Ketan K. Mane et al.

Substance Use Disorders and Comorbid Axis I and II Psychiatric Disorders Among Young Psychiatric Patients: Findings from a Large Electronic Health Records Database

Li-Tzy Wu et al.

Support for the Vascular Depression Hypothesis in Late-Life Depression: Results of a 2-Site, Prospective, Antidepressant Treatment Trial

Yvette I. Sheline et al.

Prevalence of HIV Infection in a General Psychiatric Outpatient Population

John L Beyer et al.